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1. Identity statement
Reference TypeJournal Article
Sitemtc-m21d.sid.inpe.br
Holder Codeisadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S
Identifier8JMKD3MGP3W34T/4ARCDUE
Repositorysid.inpe.br/mtc-m21d/2024/03.01.12.29   (restricted access)
Last Update2024:03.01.12.29.42 (UTC) simone
Metadata Repositorysid.inpe.br/mtc-m21d/2024/03.01.12.29.43
Metadata Last Update2024:03.16.23.14.28 (UTC) administrator
DOI10.1111/aor.14683
ISSN0160-564X
Citation KeySáAASTCMBT:2024:BiSuMi
TitleBiofunctionalization of surfaces to minimize undesirable effects in cardiovascular assistance devices
Year2024
MonthFeb.
Access Date2024, May 19
Type of Workjournal article
Secondary TypePRE PI
Number of Files1
Size2111 KiB
2. Context
Author1 Sá, Rosa Correa Leôncio de
2 Andrade, Aron José Pazin de
3 Antunes, Vagner Roberto
4 Salvadori, Cecilia
5 Teixeira, Fernanda de Sá
6 Corat, Evaldo José
7 Moro, João Roberto
8 Bock, Eduardo Guy Perpetuo
9 Trava-Airoldi, Vladimir Jesus
Resume Identifier1
2
3
4
5
6 8JMKD3MGP5W/3C9JH33
ORCID1 0000-0003-0370-7506
Group1 CMS-ETES-DIPGR-INPE-MCTI-GOV-BR
2
3
4
5
6 COPDT-CGIP-INPE-MCTI-GOV-BR
7
8
9 COPDT-CGIP-INPE-MCTI-GOV-BR
Affiliation1 Instituto Nacional de Pesquisas Espaciais (INPE)
2 Instituto de Cardiologia Dante Pazzanese
3 Universidade de São Paulo (USP)
4 Universidade de São Paulo (USP)
5 Universidade de São Paulo (USP)
6 Instituto Nacional de Pesquisas Espaciais (INPE)
7 Instituto Federal de Educação, Ciência e Tecnologia de São Paulo (IFSP)
8 Instituto Federal de Educação, Ciência e Tecnologia de São Paulo (IFSP)
9 Instituto Nacional de Pesquisas Espaciais (INPE)
Author e-Mail Address1 rosacldesa@gmail.com.br
2
3
4
5
6 evaldo.corat@inpe.br
7
8
9 vladimir.airoldi@inpe.br
JournalArtificial Organs
Volume48
Number2
Pages141-149
Secondary MarkA1_ENGENHARIAS_IV A2_INTERDISCIPLINAR B1_SAÚDE_COLETIVA B1_QUÍMICA B1_ODONTOLOGIA B1_MEDICINA_III B1_MEDICINA_II B1_MEDICINA_I B1_MATERIAIS B1_FARMÁCIA B1_ENGENHARIAS_III B1_ENGENHARIAS_I B1_CIÊNCIAS_BIOLÓGICAS_I B2_CIÊNCIAS_BIOLÓGICAS_II B2_BIOTECNOLOGIA B2_ASTRONOMIA_/_FÍSICA C_ENGENHARIAS_II
History (UTC)2024-03-01 12:31:11 :: simone -> administrator :: 2024
2024-03-16 23:14:28 :: administrator -> simone :: 2024
3. Content and structure
Is the master or a copy?is the master
Content Stagecompleted
Transferable1
Content TypeExternal Contribution
Version Typepublisher
KeywordsDLC coating
hemocompatibility
pseudo-neointimal and in vivo evaluation
ventricular assist devices
wettability
AbstractBackground: The reactivity of blood with non-endothelial surface is a challenge for long-term Ventricular Assist Devices development, usually made with pure titanium, which despite of being inert, low density and high mechanical resistance it does not avoid the thrombogenic responses. Here we tested a modification on the titanium surface with Laser Induced Periodic Surface Structures followed by Diamond Like Carbon (DLC) coating in different thicknesses to customize the wettability profile by changing the surface energy of the titanium. Methods: Four different surfaces were proposed: (1) Pure Titanium as Reference Material (RM), (2) Textured as Test Sample (TS), (3) Textured with DLC 0.3μm as (TSA) and (4) Textured with 2.4μm DLC as (TSB). A single implant was positioned in the abdominal aorta of Wistar rats and the effects of hemodynamic interaction were evaluated without anticoagulant drugs. Results: After twelve weeks, the implants were extracted and subjected to qualitative analysis by Scanning Electron Microscopy under low vacuum and X-ray Energy Dispersion. The regions that remained in contact with the wall of the aorta showed encapsulation of the endothelial tissue. TSB implants, although superhydrophilic, have proven that the DLC coating inhibits the adhesion of biological material, prevents abrasive wear and delamination, as observed in the TS and TSA implants. Pseudo- neointimal layers were heterogeneously identified in higher concentration on Test Surfaces.
AreaFISMAT
Arrangement 1urlib.net > BDMCI > Fonds > Produção pgr ATUAIS > CMS > Biofunctionalization of surfaces...
Arrangement 2urlib.net > BDMCI > Fonds > Produção a partir de 2021 > CGCE > Biofunctionalization of surfaces...
Arrangement 3urlib.net > BDMCI > Fonds > Produção a partir de 2021 > CGIP > Biofunctionalization of surfaces...
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4. Conditions of access and use
Languageen
Target FileArtificial Organs - 2023 - Sa - Biofunctionalization of surfaces to minimize undesirable effects in cardiovascular.pdf
User Groupsimone
Reader Groupadministrator
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Visibilityshown
Read Permissiondeny from all and allow from 150.163
Update Permissionnot transferred
5. Allied materials
Mirror Repositoryurlib.net/www/2021/06.04.03.40.25
Next Higher Units8JMKD3MGPCW/3F358GL
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8JMKD3MGPCW/46KUES5
Citing Item Listsid.inpe.br/bibdigital/2013/10.14.21.39 1
sid.inpe.br/bibdigital/2022/04.03.17.52 1
Host Collectionurlib.net/www/2021/06.04.03.40
6. Notes
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